A manuscript in the hand of 'David ap Griffith effyriad' (see pp. 13, 14) containing medical precepts and prescriptions (pp. 15-27, 54-92), material of botanological (pp. 28-40), physiological (pp. 41-49) and theological (pp. 1-12) interest, and poetry (pp. 13-14, 50-53). The section on botany includes a Latin-Welsh vocabulary of plant names. Poetical works cited are those of Taliesin, Dafydd ap Gruffydd and Gruffudd Gryg.
There are traces of the hand of Sir Thomas Wilems (p. 40), and also of another hand on many folios.