Forty-four loose leaves (many imperfect and stained) and a fragment containing miscellaneous material in a number of ?late sixteenth and seventeenth century hands. The contents include notes in English and Welsh on palmistry; transcripts, largely incomplete, of Welsh poems in strict and free metres by ? Owen Jones, Griff. ap Dd. Fychan, ? Willi[am] ffylyp, Dd. Llwyd ?Lln. ap Owain, Robin Ddu o Fôn, David Lloyd ap Lln. ap Griffith, Thomas Price, Owen Gwynedd, Wiliam Llyn, Sowdwal, Siôn Keri, Siôn Tudur, Tomas Brydydd, Doctor Siôn Kent, Siôn ap Howel, Gruffudd Hiraethoc, Rys Kain, and Edw[a]rt Maelor; transcripts of two 'englynion', one in English and one in Latin; etc. The inscription 'Hwn o Lyfr Meyryg Dafydd, July 1821' (in the hand of Edward Williams) appears in the volume.

The manuscript is in two parts. The first part comprises charms, directions on how to make circles, a copy of John Leland's Epigrams, problems, memoranda, Welsh verses, and a list of owners of Welsh manuscripts, apparently compiled by John Jones, Gellilvydy about 1611. The second part is a fifteenth-century treatise on palmistry, with diagrams.